Sulphaguanidine in Bacillary Dysentery

Comparative Value of Sulphadiazine and Sulphaguanidine in the Treatment of Acute Bacillary Dysentery

With the multiplicity of drugs of the sulpha group, the necessity for a study of comparative value of different members of this1 group is obvious. The present paper deals with the comparative value of sulphadiazine and sulphaguanidine in the treatment of acute bacillary dysentery. A study was started with the plan to treat alternate cases of bacillary dysentery with sulphadiazine (group ' A') a...

Bacillary Dysentery in Cyprus

The severity of the illness varied from a few loose stools to the passage of bloody fl.uid up to fifty times per day. Other symptoms included fever, nausea, occasional vomiting and abdominal cramps. There was no obvious relationship 'between the severity of the symptoms and the organism isolated. Abdominal tenderness was a common physical sign. Prostration and dehydration were surprisingly infr...

Chemotherapy in Bacillary Dysentery

Chemotherapy in Bacillary Dysentery

on them. They were treated with sulphanilamide; some of them cleared up within seven to fourteen days and others showed no improvement. These resistant cases were then given sulphapyridine (M.&B. 693) and they all cleared up within four or five days. It appeared from these observations that:? 1. Sulphanilamide is effective against some of the organisms of bacillary dysentery. 2. Sulphapyridine ...

Bacillary Dysentery in Human Volunteers *

In connection with a study to determine whether man could be successfully immunized against bacillary dysentery it was necessary to determine the infective dose of dysentery bacilli by feeding living Shigella to human volunteers. The only previous information concerning the susceptibility of man to experimental infection is contained in a few published observations' 3 of accidental laboratory-i...